I have to take advil when my pain level is extremely high but another supplement that I started to use recently is SAMe. I had bought the SAMe and not taken it when I found out my dog needed it. Rather than paying a high amount for SAMe that I already had, I started him on the stuff I bought from iHerb. I then started taking it myself. I found that the SAMe seemed to improve my mental clarity. At this point, I need all I can get!
The number of supplements have grown over the years to include a multi-vitamin, B-Complex with methyl-B12, Jarrow folate, Ubiquinol, Magnesium Malate, Calcium Citrate, D3, EFA/DHA, Glucosamine/Chondroitin, gingko biloba, and.....
I'm sure I'm missing something but I need to get to bed!
IMHO, one supplement is not going to do it for me.
ETA: I googled SAMe and glutathione because I knew SAMe somehow increased glutathione levels. One site had some great information on supplements and it describes glutathione as the "Master Anti-oxident". I also noticed another supplement -PPC. It caught my attention because it mentioned phospholipids and cell membranes. There was a discussion somewhere about phospholipids and cardiolipin so that piqued my interest. Here is the link: http://www.ei-resource.org/treatment-options/treatment-information/antioxidants-and-liver-supplements/